Supplementary Materialsmmc1. to 30% from the repertoire, steady diversity indices exposed these transient clonal distortions didn’t trigger long-term repertoire imbalance. Phenotypically, the T-cell program did not display evidence for intensifying exhaustion. Coupled with immunoglobulin substitution, the limited T-cell program in this individual backed an unremarkable medical program over 18 years. Interpretation Hereditary correction in the … Continue reading Supplementary Materialsmmc1